ARA-290 10mg

Description

ARA-290 (Cibinetide) | 10mg | Tissue Protection Research Peptide

Description

ARA-290 (Cibinetide) is a synthetic peptide derived from the B-helix region of erythropoietin (EPO). It was designed to preserve the tissue-protective and anti-inflammatory signaling characteristics of erythropoietin while minimizing erythropoietic activity associated with red blood cell production.

In laboratory research, ARA-290 is primarily investigated for its interaction with the innate repair receptor (IRR), a heterodimeric receptor complex composed of EPOR and CD131 subunits. Activation of this receptor has been associated in experimental models with cellular protection mechanisms, modulation of inflammatory signaling pathways, and support of nerve regeneration processes.

Because of its selective receptor activity, ARA-290 is frequently used in studies exploring inflammatory response regulation, neuropathic signaling pathways, and cellular recovery following stress or injury in controlled in vitro environments.

This vial contains 10mg of lyophilized ARA-290 peptide intended strictly for controlled in vitro laboratory research applications.

Specifications

• Compound: ARA-290 (Cibinetide)
• Unit Size: 10mg (lyophilized powder, single vial)
• Sequence: MTRLYERAEVHEHQEAWHEQL
• Molecular Formula: C124H205N39O41
• Molecular Weight: ~2885.2 Da
• Form: Crystalline lyophilized peptide powder
• Solubility: Soluble in sterile water or compatible aqueous buffers according to laboratory protocols
• Storage: Store lyophilized material at 2–8 °C in a sealed container protected from light and moisture

Research Applications

Innate Repair Receptor Signaling Research

ARA-290 is widely studied in laboratory models examining activation of the innate repair receptor (IRR), which consists of EPOR and CD131 receptor components. Researchers investigate how this receptor system influences cellular protection and inflammatory signaling processes.

Inflammatory Pathway Modulation Research

Experimental systems frequently utilize ARA-290 to explore modulation of pro-inflammatory cytokine pathways and cellular immune signaling responses in controlled laboratory environments.

Neural Protection and Regeneration Research

Researchers commonly study ARA-290 in models focused on neural tissue recovery and nerve signaling pathways. These studies examine how IRR activation may influence cellular repair and neuronal resilience in experimental conditions.

Tissue Recovery and Cellular Stress Response Research

ARA-290 is also utilized in research examining cellular responses to stress, injury, or inflammation. Laboratory models investigate how peptide signaling may influence tissue protection and cellular recovery mechanisms.

Receptor-Mediated Cytoprotection Research

Because ARA-290 selectively activates non-erythropoietic signaling pathways, it is frequently used in receptor binding and cytoprotection studies aimed at understanding the biological effects of EPO-derived peptides without red blood cell stimulation.

Intended Use

in vitro laboratory research use only

Legal Disclaimer

This product has not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding the treatment, diagnosis, cure, or prevention of any disease. All information provided is intended strictly for scientific and educational purposes only.

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